- Disease
Presence
and frequency of the Helicobacter Pylori (HP) as etiologic agent has
been noticed more and more often in active chronic gastritis, implicated
in most gastric and duodenal ulcer cases and in development of correlated
carcinomas and lymphomas
(cagA+
strain)
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- Technique
Detection
via HP genome ureC gene amplification and identification of cagA+ gene
via amplification of a specific sequence of the gene.
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- Advantages
HP direct
identification carried out with non - invasive but highly sensitive
and specific methods like saliva not only provides a precise diagnosis
of infection but also the assessment of the response via eradication
therapy.
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- Samples
DNA
taken from saliva samples or "fresh" tissue. Preservation at 4°C over
a 24 - hour period or at -20°C for a longer period.
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